Home Cage Testing of Decision-Making

نویسندگان

  • Susanne Koot
  • Ruud van den Bos
  • Gianni Laviola
چکیده

Testing rodents in their home cages has become increasingly popular. A new low-cost computer-controlled operant panel was designed, which can be placed inside the home cage. A pilot study was carried out, using a decisionmaking protocol, which was adapted from the original maze rodent Iowa Gambling Task (r-IGT). Male adult rats were tested in their home cages, containing the operant panel provided with nose-poking holes. Nose-poking was associated with rewards of different value and probability. A tryptophan-free diet was fed to investigate the effect of lowering central serotonin concentration on performance in the r-IGT. The data suggested that control rats behave in a way similar to rats tested in the original r-IGT; that is, they tend to choose the option with the best long-term payoff more often as the test progresses. Tryptophan depleted rats showed a weaker improvement across trials than controls.

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

منابع مشابه

Elderly Daily Activity-Based Mood Quality Estimation Using Decision-Making Methods and Smart Facilities (Smart Home, Smart Wristband, and Smartphone)

Due to the growth of the aging phenomenon, the use of intelligent systems technology to monitor daily activities, which leads to a reduction in the costs for health care of the elderly, has received much attention. Considering that each person's daily activities are related to his/her moods, thus, the relationship can be modeled using intelligent decision-making algorithms such as machine learn...

متن کامل

Fuzzy decision making in testing hypotheses: An introduction to the packages ``FPV" and ``Fuzzy.p.value" with practical examples

This paper reviews and compares two R packages ``FPV" and ``Fuzzy.p.value".These packages are designed for testing hypotheses in a fuzzy environment using a fuzzy $p$-value based approach.In fact, the packages ``FPV" and ``Fuzzy.p.value" propose some useful functions for testing hypotheses when the data / hypotheses are fuzzy rather than crisp.The proposed methods and function...

متن کامل

Fighting in the home cage: Agonistic encounters and effects on neurobiological markers within the social decision-making network of house mice (Mus musculus).

Inbred strains of mice, such as C57Bl/6, have become preferred animal models for neurobehavioral studies. A main goal in creating inbred lines is to reduce the effects of individual genetic variation on observed phenotypes. Most studies use only males, and there is increasing evidence that agonistic interactions within the home cage may produce systematic variability in behavior and brain funct...

متن کامل

Evaluation and Prioritization of Criteria Affecting the Selection of Landscape Species, Using Multi-Criteria Decision-Making Systems

It is impractical to implement conservation efforts for all species due to complexity of natural systems, large scale of biodiversity issues, and budget limitations. Prioritizing species of conservation importance can alleviate this issue. Multiple interrelated criteria may be used for conservation prioritization of species. Therefore, the accurate evaluation of criteria is a multi-criteria dec...

متن کامل

Investigating the Effectiveness of Teacher's Ethical Decision Making on Professional Ethics of Managers Based on the Mediating Role of Infor-mation Literacy: A Case Study

Background and Aim: The purpose was to analyze the effect of administrators professional ethics on teacherschr('39') ethical decision making by examining the mediating role of information literacy among teachers in the second district of Urmia. Method: Study is a descriptive, correlational survey.  Population comprised of  982 teachers in District 2, of which 262 were selected by simple random ...

متن کامل

ذخیره در منابع من


  با ذخیره ی این منبع در منابع من، دسترسی به آن را برای استفاده های بعدی آسان تر کنید

برای دانلود متن کامل این مقاله و بیش از 32 میلیون مقاله دیگر ابتدا ثبت نام کنید

ثبت نام

اگر عضو سایت هستید لطفا وارد حساب کاربری خود شوید

عنوان ژورنال:

دوره   شماره 

صفحات  -

تاریخ انتشار 2010